First prospective, multi-centre clinical experience with a novel left ventricular quadripolar lead

• DOI: 10.1093/europace/eur322
• Publication Date: 2011-10-12T20:34:38Z
• Authors: J. Sperzel; W. Danschel; K.-J. Gutleben; W. Kranig; P. Mortensen; D. Connelly; H.-J. Trappe; K. Seidl; G. Duray; B. Pieske; J. Stockinger; G. Boriani; W. Jung; R. Schilling; L. Saberi; B. Hallier; M. Simon; C. A. Rinaldi
• Keywords: Lead (geology)

Cardiac resynchronization therapy (CRT) is sometimes complicated by elevated pacing thresholds and phrenic nerve stimulation (PNS), both of which may require that the coronary sinus lead be repositioned. The purpose this study was to evaluate performance a novel quadripolar electrode cardiac therapy-defibrillator (CRT-D) device enables electrical repositioning, potentially obviating reposition procedure. Patients indicated for CRT were enrolled received CRT-D (Quartet®model 1458Q Promote Q®; St Jude Medical, Sylmar, CA, USA). Electrical data, presence PNS during from each left ventricular (LV) configuration, documented at pre-hospital discharge 1 month. Seventy-five patients 71 successfully implanted with Quartet®lead. measurements stable over follow-up period. Ninety-seven per cent (64 66) had one or more programmable configurations threshold <2.5 V no vs. 86% (57 if only conventional bipolar considered. Physicians able use increased programming options manage changes PNS. new LV provides address common problems faced when managing patients. vectors are comparable configurations. Furthermore, 11% in suffered on all vectors.