PS195. Reduced cerebrospinal fluid ethanolamine concentration in major depressive disorder

• DOI: 10.1093/ijnp/pyw043.195
• Publication Date: 2017-02-03T14:34:22Z
• Authors: Shintaro Ogawa; Kotaro Hattori; Teruhiko Higuchi; Hiroaki Hori; Hiroshi Kunugi; Ryo Matsumura; Junko Matsuo; Nobutaka Motohashi; Takamasa Noda; Yoshiaki Ohashi; Miho Ota; Daimei Sasayama; Hajime Satō; Toshiya Teraishi; Yuki Yokota; Sumiko Yoshida

71groups, only KYN correlated with SERT in the midbrain HC (ρ=-0.544,p=0.001).A further analysis showed that, at TBI > 0.06, TRP (ρ=-0.900,p=0.037),KYN (ρ=-0.900,p=0.037), and (ρ=0.900,p=0.037) HC.However, this could not be replicated MDD. Conclusion:Our results are first to demonstrate complicated interactions between metabolism different brain regions.The significance of association HC, particular levels TBI, is warrant for study.