In-vitro comparison of the postantibiotic effect of vancomycin and teicoplanin

• DOI: 10.1093/jac/26.2.203
• Publication Date: 2007-01-04T18:10:06Z
• Authors: M. A. Cooper; Y.-F. Jin; J. P. Ashby; J. M. Andrews; R. Wise
• Keywords: Teicoplanin; Enterococcus faecalis; Gram-Positive Cocci

The post-antibiotic effect (PAE) of teicoplanin was compared with that vancomycin for five selected Gram-positive cocci. Two concentrations each antibiotic were investigated, the test organisms being exposed to both 1 and 2 h. At a concentration 25 mg/l, had greater PAE than methicillin resistant staphylococci Enterococcus faecalis strains tested. 5 gave equal effects those except strain methicillin-resistant Staphylococcus aureus (MRSA) variation in exposure time only small changes PAE, MRSA