Strathclyde minor groove binders (S-MGBs) with activity against Acanthamoeba castellanii

• DOI: 10.1093/jac/dkae221
• Publication Date: 2024-07-09T16:53:03Z
• Authors: Leah M C Mcgee; Alemao G Carpinte...; Marina Perieteanu; Kaveh Eskandari; Yan Bian; Logan Mackie; Louise Young; Rebecca Beveridge; Colin J Suckling; Craig W Roberts; Fraser J Scott
• Keywords: Acanthamoeba keratitis

Acanthamoeba spp. is the causative agent of keratitis and granulomatous amoebic encephalitis. Strathclyde minor groove binders (S-MGBs) are a promising new class anti-infective that have been shown to be effective against many infectious organisms.