Proposal for assignment of allele numbers for mobile colistin resistance (mcr) genes

• DOI: 10.1093/jac/dky262
• Publication Date: 2018-06-22T07:51:53Z
• Authors: Sally R Partridge; Vincenzo Di Pilato; Yohei Doi; Michael Feldgarden; Daniel H Haft; William Klimke; Samir Kumar-Singh; Jian-Hua Liu; Surbhi Malhotra-K...; Arjun Prasad; Gian Maria Rossolini; Stefan Schwarz; Jianzhong Shen; Timothy Walsh; Yang Wang; Basil Britto Xavier
• Keywords: Gene nomenclature; Confusion

The initial report of the mcr-1 (mobile colistin resistance) gene has led to many reports variants and other mcr genes from different bacterial species originating human, animal environmental samples in geographical locations. Resistance nomenclature is complex unfortunately problems such as names being used for same gene/protein or name genes/proteins are not uncommon. Registries exist some families, bla (β-lactamase) genes, but there yet no agreed scheme genes. National Center Biotechnology Information (NCBI) recently took over assigning allele numbers longstanding Lahey β-lactamase website do Here, we propose a that hope will be acceptable researchers this area reduce future confusion.