Altered chromatin architecture and gene expression during polyploidization and domestication of soybean

• DOI: 10.1093/plcell/koab081
• Publication Date: 2021-03-13T12:10:32Z
• Authors: Longfei Wang; Guanghong Jia; Xinyu Jiang; Shuai Cao; Z Jeffrey Chen; Qingxin Song
• Keywords: Glycine soja

Abstract Polyploidy or whole-genome duplication (WGD) is widespread in plants and a key driver of evolution speciation, accompanied by rapid dynamic changes genomic structure gene expression. The 3D the genome intricately linked to expression, but its role transcription regulation following polyploidy domestication remains unclear. Here, we generated high-resolution (∼2 kb) Hi-C maps for cultivated soybean (Glycine max), wild soja), common bean (Phaseolus vulgaris). We found polyploidization may induce architecture topologically associating domains subsequent diploidization led chromatin topology alteration around chromosome-rearrangement sites. Compared with single-copy small-scale duplicated genes, WGD genes displayed more long-range chromosomal interactions were coupled higher levels expression accessibilities void DNA methylation. Interestingly, loop reorganization was involved divergence during domestication. Genes loops under stronger artificial selection than without loops. These findings provide insights into roles structures on polyploidization, diploidization, soybean.