HISTONE DEACETYLASE 6 suppresses salicylic acid biosynthesis to repress autoimmunity

• DOI: 10.1093/plphys/kiab408
• Publication Date: 2021-08-30T14:03:35Z
• Authors: Zhenjiang Wu; Lei He; Ye Jin; Jing Chen; Huazhong Shi; Yizhong Wang; Wannian Yang
• Keywords: Plant Immunity; Systemic Acquired Resistance

Abstract Salicylic acid (SA) plays an important role for plant immunity, especially resistance against biotrophic pathogens. SA quickly accumulates after pathogen attack to activate downstream immunity events and is normally associated with a tradeoff in growth. Therefore, the level plants has be strictly controlled when pathogens are absent, but how this occurs not well understood. Previously we found that Arabidopsis (Arabidopsis thaliana), HISTONE DEACETYLASE 6 (HDA6), negative regulator of gene expression, essential since its mutation allele shining 5 (shi5) exhibits autoimmune phenotypes. Here report mainly through suppression biosynthesis: first, phenotypes higher Pst DC3000 shi5 mutants depended on SA; second, significantly accumulated mutants; third, HDA6 repressed biosynthesis by directly controlling expression CALMODULIN BINDING PROTEIN 60g (CBP60g) SYSTEMIC ACQUIRED RESISTANCE DEFICIENT 1 (SARD1). bound chromatin CBP60g SARD1 promoter regions, histone H3 acetylation was highly enriched within these regions. Furthermore, transcriptome mimicked treated exogenous or attacked All data suggest vital finely regulate immunity.