Neuronal calcium sensor 1 (NCS1) promotes motility and metastatic spread of breast cancer cells in vitro and in vivo

• DOI: 10.1096/fj.201802004r
• Publication Date: 2018-12-28T19:59:32Z
• Authors: Jonathan E. Apasu; Daniel Schuette; Ryan Laranger; Julia A. Steinle; Lien D. Nguyen; Henrike K. Grosshans; Meiling Zhang; Wesley L. Cai; Qin Yan; Marie E. Robert; Michael Mak; Barbara E. Ehrlich
• Keywords: 0303 health sciences; Reverse Transcriptase Polymerase Chain Reaction; Neuronal Calcium-Sensor Proteins; Neuropeptides; Mice, Nude; Breast Neoplasms; Xenograft Model Antitumor Assays; 3. Good health; Mice; 03 medical and health sciences; Microscopy, Fluorescence; Cell Line, Tumor; Animals; Humans; Female; Cell Proliferation

1.4.8Lung histology confirms higher tumor burden in mice xenografted with NCS1 overexpressing cells 1.4.9NCS1 protects cancer from necrosis within mature tumors 1.5 Discussion 1.