WHEN TO SEARCH FOR CEREBROVASCULAR LESIONS IN PATIENTS WITH RENAL ARTERY FIBROMUSCULAR DYSPLASIA

• DOI: 10.1097/01.hjh.0000572012.04902.35
• Publication Date: 2019-06-22T17:25:06Z
• Authors: M. Pappaccogli; E. Warchol-Celinska; L. Swiatlowski; A. Prejbisz; F. Elzbieta; J.P. Katarzyna; P. Talarowska; M. Januszewicz; P. Dobrowolski; A. Klisiewicz; I. Michalowska; J. Kadziela; A. Witkowski; A. Tykarski; A. Falkowski; A. Januszewicz; M. Szczerbo-Troja...; A. Persu
• Keywords: Fibromuscular Dysplasia; Arcadia; Concomitant

Objective: Previous reports have shown a high prevalence of concomitant renal and cerebrovascular Fibromuscular Dysplasia (FMD). However, systematic whole body CT scan was performed in only few studies. Furthermore, distinctive features patients with or without FMD not been reported detail. The aim this study to assess the involvement included ARCADIA-POL look for differences between involvement. Design method: We reviewed all ARCADIA-POL. Only those confirmed diagnosis were eligible analysis. All underwent detailed evaluation including CTA from brain pelvis. Cerebrovascular defined as presence any following lesions: stenosis, aneurysm, dissection and/or S-shaped cervical artery. Results: Of 203 (84% women, age at diagnosis: 42.1 ± 15.7 yo), 29% (n = 58) had FMD, among whom 45% harboured intracranial aneurysms. When compared overwhelmingly multifocal subtype (93% vs. 75%, p 0.004), older (46.3 40.4 yo. 0.01) more frequently smokers (35% 21%; 0.046). They also presented often bilateral 17%, 0.002) third vascular bed (36% 4%, < 0.001). Conclusions: In registry, lower than previous Notably however, almost half them cerebral Patients subtype, lesions widespread disease. Screening should be prioritized subtype. interest screening focal is questionable.