MP36-19 WHAT IS THE ACCURACY OF 68 GA-PSMA PET/CT IN DETECTING PRIMARY PROSTATE CANCERS COMPARED TO MULTIPARAMETRIC MRI?

• DOI: 10.1097/01.ju.0000556029.10817.c5
• Publication Date: 2019-04-24T05:40:57Z
• Authors: Yen-Cheng Henry Pan*; Arveen A. Kalapara; Daniel Moon; Uri Hanegbi; Adam Landau; Ross Snow; Richard O'Sullivan; Andrew Ryan; Mark Frydenberg; Jeremy Grummet
• Keywords: Multiparametric MRI

You have accessJournal of UrologyProstate Cancer: Detection & Screening V (MP36)1 Apr 2019MP36-19 WHAT IS THE ACCURACY OF 68GA-PSMA PET/CT IN DETECTING PRIMARY PROSTATE CANCERS COMPARED TO MULTIPARAMETRIC MRI? Yen-Cheng Henry Pan*, Arveen A. Kalapara, Daniel Moon, Uri Hanegbi, Adam Landau, Ross Snow, Richard O'Sullivan, Andrew Ryan, Mark Frydenberg, and Jeremy Grummet Pan*Yen-Cheng Pan* More articles by this author , KalaparaArveen Kalapara MoonDaniel Moon HanegbiUri Hanegbi LandauAdam Landau SnowRoss Snow O'SullivanRichard O'Sullivan RyanAndrew Ryan FrydenbergMark Frydenberg GrummetJeremy View All Author Informationhttps://doi.org/10.1097/01.JU.0000556029.10817.c5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: PSMA has demonstrated superior sensitivity in detecting prostate cancer metastases compared traditional staging modalities seen a high degree utilisation the Australian setting. However, there is little data published on role diagnosing primary cancer. We accuracy multiparametric MRI for detection clinically significant METHODS: A local prospective database (REDCap-Monash) was maintained patients who underwent our group urology practice from July 2013 December 2017. had an diagnosis cancer, subsequent transperineal biopsy, initial were included, with being defined as greater than or equal Gleason 3+4=7 (ISUP Grade Group 2). RESULTS: The contained 2,283 MRI. 239 subsequently both biopsy PET/CT. 202 biopsies (84.5%) showed Of non-significant cases, 21 (8.8%) revealed 1 lesions 16 (6.7%) benign. For cancers, 189 scans avidity prostate, 174 positive (PIRADS 4 5) scans. detected fewer insignificant but resulted more false negatives. Overall, specificity respectively 93.6%, 64.9% 87.1%, 70.3%. CONCLUSIONS: In highly-selected cohort undergoing MRI, part clinical practice, outperformed It proposed that PET may be used cancers staging, although cost-effectiveness dual warrants further investigation. Higher achieved comes at expense disease, evidenced higher false-positive rates. Furthermore, soft-tissue resolution anatomical detail inferior Source Funding: none Melbourne, Australia© 2019 American Urological Association Education Research, Inc.FiguresReferencesRelatedDetails Volume 201Issue Supplement 4April 2019Page: e521-e522 Advertisement Copyright Permissions© Inc.MetricsAuthor Information Expand PDF downloadLoading ...