CLINICAL PRESENTATION AND LONG TERM OUTCOME OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN AND ADOLESCENTS

• DOI: 10.1097/01.mpg.0000181890.04726.f7
• Publication Date: 2005-10-04T08:02:30Z
• Authors: Grace I Onimoe; Vasundhara Tolia; Ron Thomas
• Keywords: Esophagogastroduodenoscopy; Heartburn

Objective: A retrospective review of pediatric patients diagnosed with GERD long term follow up to study presenting symptoms, associated conditions, response treatment and need step or down from initial treatment. Design/Methods: Chart was performed on by Esophagogastroduodenoscopy (EGD) biopsy. Duration Histamine receptor antagonists (H2RAS) Proton pump inhibitors (PPIS), for if Rx discontinued assessed. Inclusion Criteria: Children >2 yrs at diagnosis. Exclusion neurologic esophageal anatomic abnormalities. Results: 54 (28 Females), ages ranging 2.5 17 years (mean ± SD-8.55 4.34) were identified. The most common symptoms chronic abdominal pain (61.1%),Vomiting (14.9%) heartburn (5.6%). 8 had asthma. BMI range 13.80 42.80 = 22.34). After a one four year period 3.27), all responded its modifications. 32 started H2RAS 22 PPIS. the second Rx, 9 stepped PPIS, while 2 PPIS H2RAS, thereafter 12 lost up. sequential data are shown in Table 1 2.TABLE 1: PPIS- patientsTABLE 2: H2RAS- patientsConclusion: Longitudinal suggests that continuous is needed even absence other predisposing factors normal children age GERD. Prospective Long Term studies understand natural history Children.