Acute Hemorrhagic Leukoencephalitis

• DOI: 10.1097/01.rct.0000173843.82364.db
• Publication Date: 2005-09-14T09:40:04Z
• Authors: Wende N Gibbs; Mahmoud A Kreidie; Ronald C Kim; Anton N Hasso
• Keywords: Fulminant; Coma (optics); Susceptibility Weighted Imaging; Cerebral edema; Demyelinating disease; Brain biopsy

A case of biopsy-proven acute hemorrhagic leukoencephalitis is reported. The early computed tomography scans showed extensive bilateral hypodensities with mass effects and foci microhemorrhages. Bilateral asymmetric hyperintensities in the mesiotemporal frontal lobes massive edema were found on T2-weighted fluid-attenuated inversion recovery magnetic resonance images a pattern classic for herpes simplex encephalitis. This fulminant demyelinating disease progresses to coma death within days. Early diagnosis neuroimaging studies rapid correlation clinical findings this are vital institution potentially lifesaving treatments.