Cerebral Perfusion Pressure Below 60 mm Hg is Common in the Intraoperative Setting

• DOI: 10.1097/ana.0b013e31822b4f05
• Publication Date: 2011-10-04T20:25:40Z
• Authors: Laurel E. Moore; Milad Sharifpour; Amy Shanks; Sachin Kheterpal; Kevin K. Tremper; George A. Mashour
• Keywords: Interquartile range; Mean arterial pressure

Maintaining adequate cerebral perfusion pressure (CPP) is of clinical concern in patients with neurological injury. Although there are extensive data on CPP the ICU setting, has been little quantitative study intraoperative setting.We retrospectively analyzed electronic records neurosurgical and trauma concurrent intracranial arterial monitoring devices continuous use for ≥45 minutes to calculate (=mean pressure-intracranial pressure). We assessed total frequency 5-minute epochs, during which median was <60 mm Hg, associated risk factors.A 155 were studied. In neurosurgery cohort (n=88), 74% had at least one epoch Hg CPP<60 39 [interquartile range (67), length surgery 274 (300) min]. (n=67), 82% 35 [(59), 159 (160) For entire (n=155), found have higher compared CPP≥60 (P<0.001). Unlike cohort, a greater episodes mean <70 (P=0.001).CPP<60 common setting tertiary medical center 2 different surgical populations pathology. Prospective studies outcomes warranted.