Reevaluation of Discriminatory and Threshold Levels for Serum β-hCG in Early Pregnancy

• DOI: 10.1097/aog.0b013e318278f421
• Publication Date: 2015-10-13T18:40:27Z
• Authors: AnnaMarie Connolly; David H. Ryan; Alison M. Stuebe; Honor M. Wolfe
• Keywords: Vaginal bleeding

In Brief OBJECTIVES: To reevaluate both discriminatory and threshold levels associated with visualization of gestational sacs, yolk fetal poles in patients presenting vaginal bleeding, pain, or bleeding pain the first trimester pregnancy using current ultrasonographic technology. METHODS: We reviewed records first-trimester pelvic who were evaluated a serum β-hCG level transvaginal ultrasonogram within 6 hours each other had known outcome. Discriminatory for sac, pole identified all ultimately viable pregnancies. Logistic regression was used to model predicted probability visualizing these structures as function values fractional polynomials. RESULTS: Six hundred fifty-one pregnancies met inclusion criteria; 366 viable. at which would be seen 99% time 3,510 milli-international units/mL, 17,716 47,685 units/mL pole, respectively. our population, could 390 1,094 1,394 CONCLUSIONS: Improvements technology have led lower early intrauterine structures. However, higher than currently practice. LEVEL OF EVIDENCE: II β-human chorionic gonadotropin are