Epidemiology and risk factors of sepsis after multiple trauma: An analysis of 29,829 patients from the Trauma Registry of the German Society for Trauma Surgery*

• DOI: 10.1097/ccm.0b013e318206d3df
• Publication Date: 2011-01-18T06:44:21Z
• Authors: Arasch Wafaisade; Rolf Lefering; Bertil Bouillon; Samir G. Sakka; Oliver C. Thamm; Thomas Paffrath; Edmund Neugebauer; Marc Maegele
• Keywords: Major trauma; Trauma surgery; Revised Trauma Score

The objectives of this study were 1) to assess potential changes in the incidence and outcome sepsis after multiple trauma Germany between 1993 2008 2) evaluate independent risk factors for posttraumatic sepsis.Retrospective analysis a nationwide, population-based prospective database, Trauma Registry German Society Surgery.A total 166 voluntarily participating centers (levels I-III).Patients registered Surgery with complete data sets who presented relevant load (Injury Severity Score ≥ 9) admitted an intensive care unit (n = 29,829).None.Over 16-yr period, 10.2% (3,042 29,829) multiply injured patients developed during their hospital course. Annual summarized into four subperiods: 1993-1996, 1997-2000, 2001-2004, 2005-2008. incidences subperiods 14.8%, 12.5%, 9.4%, 9.7% (p < .0001), respectively. In-hospital mortality all decreased respective (16.9%, 16.0%, 13.7%, 11.9%; p .0001). For subgroup sepsis, rates 16.2%, 21.5%, 22.0%, 18.2% .054), following calculated from multivariate logistic regression analysis: male gender, age, preexisting medical condition, Glasgow Coma Scale score ≤ 8 at scene, Injury Score, Abbreviated ScaleTHORAX 3, number injuries, red blood cell units transfused, operative procedures, laparotomy.The significantly over period; however, decade remained unchanged. Although overall has declined since 1993, there been no significant decrease septic patients. Thus, challenging complication past 2 decades. Recognition identified may guide early diagnostic workup help reduce complications trauma.