Metastatic Merkel Cell Carcinoma With Positive Expression of Thyroid Transcription Factor-1-A Case Report

• DOI: 10.1097/dad.0b013e31819821e8
• Publication Date: 2009-05-21T09:54:30Z
• Authors: Adam Sierakowski; Khalid Al-Janabi; Helena van Dam; Manu Sood
• Keywords: Skin Neoplasms; Biopsy; Thyroid Nuclear Factor 1; Nuclear Proteins; Immunohistochemistry; 3. Good health; Carcinoma, Merkel Cell; 03 medical and health sciences; 0302 clinical medicine; Biomarkers, Tumor; Humans; Female; Aged; Transcription Factors

We report on a case of metastatic Merkel cell carcinoma in a 74-year-old patient with positive staining for thyroid transcription factor-1. This represents a new immunohistochemical staining pattern for Merkel cell carcinoma and has implications regarding the accurate diagnosis of this tumor type.