Bone mineral density, arterial stiffness, and coronary atherosclerosis in healthy postmenopausal women

• DOI: 10.1097/gme.0b013e3181a15552
• Publication Date: 2009-08-29T07:14:00Z
• Authors: Seok Kyo Seo; SiHyun Cho; Hye Yeon Kim; Young Sik Choi; Ki Hyun Park; Dong Jae Cho; Byung Seok Lee
• Keywords: Coronary atherosclerosis

The aim of this study was to assess the correlation between bone mineral density (BMD), arterial stiffness, and coronary atherosclerosis in healthy postmenopausal women.We performed a retrospective review 152 women who visited health promotion center for routine checkup, after excluding participants had factors affecting BMD artery disease. evaluated by dual-energy x-ray absorptiometry lumbar spine femur. Arterial stiffness measured brachial-ankle pulse wave velocity (baPWV), assessed 64-row multidetector computed tomography.Women with osteoporosis significantly higher baPWV than those osteopenia normal groups. Higher also associated presence atherosclerosis. positively correlated age, systolic blood pressure, diastolic neutrophil lymphocyte ratio negatively femur BMD. optimum predictive value estimated using receiver operating characteristic curve. A cutoff 1,506 cm/second would give sensitivity 83.3% specificity 82.9%. overall risk emerges levels (>1,500 cm/s) controlling age cardiovascular factors.Arterial measuring can be useful independent predictor In addition, our results suggest that should considered further evaluation