Clustering of cardiometabolic risk factors in Asian Indian women

• DOI: 10.1097/gme.0b013e3181bfac28
• Publication Date: 2010-03-02T06:51:01Z
• Authors: Minakshi Bhagat; Sangita Mukherjee; Priyanka De; Riddhi Goswami; Susil Pal; Mithun Das; Arnab Ghosh
• Keywords: Adult; India; Blood Pressure; Intra-Abdominal Fat; 03 medical and health sciences; 0302 clinical medicine; Asian People; 5. Gender equality; Risk Factors; Cluster Analysis; Humans; Aged; Metabolic Syndrome; Anthropometry; Age Factors; Middle Aged; Lipids; 3. Good health; Postmenopause; Cross-Sectional Studies; Premenopause; Cardiovascular Diseases; Female; Waist Circumference

The aim of the present cross-sectional study was to investigate clustering cardiometabolic risk factors in premenopausal and postmenopausal Asian Indian women.A total 214 healthy women (25-65 y) from Bolpur-Santiniketan area, West Bengal, India, took part study. were categorized into two groups, namely, (n = 161) 53). Anthropometric measures, minimum waist circumference (WC) sum four (biceps + triceps subscapular suprailiac) skinfolds (SF4), measured accordingly. Intra-abdominal visceral fat (IVF) also measured. Left arm systolic (SBP) diastolic (DBP) blood pressure taken participants. Metabolic profiles, cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), low-density (LDL), fasting plasma glucose (FPG), insulin, testosterone, estrogen, accordingly.The identified factor 1: WC, SF4, IVF, TC, TG; 2: HDL, SBP, DBP, insulin; 3: TG, LDL, testosterone; 4: FPG, estrogen. These cumulatively explained 72.97% phenotypic variation. In women, DBP; IVF; together 90.71% variation factors.No common underlying physiological variables indicate that a single axis for phenotypes is highly unlikely.