Benefits of physical training on exercise capacity, inspiratory muscle function, and quality of life in patients with ventricular assist devices long-term postimplantation

• DOI: 10.1097/hjr.0b013e32833c0320
• Publication Date: 2010-06-24T09:49:00Z
• Authors: Ioannis D Laoutaris; Athanasios Dritsas; Stamatis Adamopoulos; Athanassios Manginas; Aggeliki Gouziouta; Manolis S Kallist...; Maria Koulopoulou; Vasilis Voudris; Dennis V Cokkinos; Petros Sfirakis
• Keywords: Treadmill; Aerobic Exercise; Intensity; Ventilatory threshold; Respiratory minute volume

Capacity to exercise may not be fully restored in patients with heart failure even the long term after ventricular assist device (VAD) implantation. The benefits of training VAD are unknown.Fifteen patients, aged 38.3 ± 15.9 years, bridged transplantation left or biventricular were randomized at a ratio 2 : 1 group (TG, n = 10) control (n 5), 6.3 4 months Both groups advised walk 30–45 min/day. TG also underwent moderate-intensity aerobic using bike treadmill for 45 min, three five times week, combined high-intensity inspiratory muscle computer-designed software respiratory exhaustion, two week 10 weeks. tested cardiopulmonary testing, 6-min test, spirometry and electronic pressure manometer strength (Pimax) endurance (sustained Pimax) measurement. Quality life was assessed Minnesota Living Heart Failure questionnaire.TG improved peak oxygen consumption (19.3 4.5 vs. 16.8 3.7 ml/kg per P 0.008) VO2 ventilatory threshold (15.1 4.2 12 5.6 0.01), whereas ventilation/carbon dioxide slope decreased (35.9 40 6.5, 0.009). test distance increased (527 76 462 88 m, 0.005) quality (38.2 11.6 48.9 12.8, 0.005), as well Pimax (131.8 33 95.5 28cmH2O, sustained (484 195 340 193cmH2O/s/103, lung capacity (2.4 0.9 1.7 0.7 L, improved. No significant changes noted group.Our findings indicate that improve functional status recipients later period implantation thus, have additional importance cases destination therapy.