Clinical Features, Prognostic Factors, and Their Relationship With Antiplatelet Antibodies in Children With Immune Thrombocytopenia

• DOI: 10.1097/mph.0b013e3182282548
• Publication Date: 2013-06-13T21:23:26Z
• Authors: Wan-Ling Ho; Chin-Cheng Lee; Chiung-Ju Chen; Meng-Yao Lu; Fu-Chang Hu; Shiann-Tarng Jou; Dong-Tsamn Lin; Kai-Hsin Lin
• Keywords: Demographics

We investigated and evaluated the demographics, clinical laboratory features, treatment responses, disease duration of 25 children with immune thrombocytopenia (ITP) eligible for detection antiplatelet antibodies. found that patients without antecedent preceding infection (API) were more likely to have anti-GPIa/IIa than those API (42.9% vs. 5.5%, P=0.048). Age groups <2 years 2 10 show response (R) or complete (CR) given treatments, whereas none whose onset age >10 showed R CR treatments (88.9% 100% vs 0%, P=0.001). The percentage newly diagnosed ITP was higher in (100%) (90%) group (16.7%, Patients (71.4%) develop chronic (5.6%, P=0.002). In conclusion, younger a favorable prognostic factor, especially respect responses duration. addition, associated short course as well absence anti-GPIa/IIa.