A Multicenter Outcomes Analysis of Children With Severe Viral Respiratory Infection Due to Human Metapneumovirus

• DOI: 10.1097/pcc.0b013e3182720fc7
• Publication Date: 2013-02-08T08:08:45Z
• Authors: Michael C. Spaeder; Jason W. Custer; Melania M. Bembea; Devon O. Aganga; Xiaoyan Song; Susanna Scafidi
• Keywords: Metapneumovirus; 2019-20 coronavirus outbreak

To investigate the impact of human metapneumovirus on morbidity and mortality outcomes in children with severe viral respiratory infection.Retrospective cohort study.ICU, either PICU or cardiac ICU, at three urban academic tertiary care children's hospitals.All patients admitted to an ICU laboratory-confirmed infection between January 2010 June 2011.We captured demographic clinical data analyzed associated outcomes.There were 111 one participating institutions during period study. The median hospital length stay was 7 days (interquartile range 4-18 days) 4 1-10 days). Ten (9%) did not survive discharge. Predisposing factors increased included female gender (p = 0.002), presence a chronic medical condition 0.04), acquisition 0.006). Adjusting for gender, conditions, severity illness score, logistic regression analysis demonstrated that infection, conditions each independently odds (odds ratios 14.8, 10.7, 12.7, respectively).Analysis our results suggests there is substantial due children. Female increases mortality. burden from terms resource utilization may be considerable.