Poor outcome of HIV-infected patients with plasmablastic lymphoma

• DOI: 10.1097/qad.0b013e32835e069d
• Publication Date: 2013-02-23T08:56:48Z
• Authors: Philipp Schommers; Christoph Wyen; Marcus Hentrich; Daniel Gillor; Alexander Zoufaly; Bjoern Jensen; Johannes R. Bogner; Jan Thoden; Jan C. Wasmuth; Gerd Fätkenheuer; Christian Hoffmann
• Keywords: Plasmablastic lymphoma; Univariate analysis; International Prognostic Index

Out of 302 AIDS-related lymphoma (ARL) patients enrolled in the German ARL cohort study, 18 had plasmablastic (PBL). Twelve out (67%) have died with a median survival 4 months (range 0-11 months). In univariate analysis, an intermediate or high international prognostic index score was associated significantly lower overall and progression-free survival. The predominant cause death progressive (67%). Our data indicate that outcome PBL is still very poor.