Anal Human Papillomavirus Infection Among HIV-Infected and Uninfected Men Who Have Sex With Men in Beijing, China

• DOI: 10.1097/qai.0b013e31829b6298
• Publication Date: 2013-06-01T12:09:49Z
• Authors: Yifei Hu; Han-Zhu Qian; Jiangping Sun; Lei Gao; Lu Yin; Xiangwei Li; Dong Xiao; Dongliang Li; Xiaoyun Sun; Yuhua Ruan; Douglas F. Milam; Stephen W. Pan; Yiming Shao; Sten H. Vermund
• Keywords: Anal intercourse

In light of China's unique ethnic and sociocultural context, a marked rise in HIV prevalence among MSM, it is important to determine prevalence, genotypes predictors anal human papillomavirus (HPV) HIV-infected uninfected men who have sex with (MSM) Beijing, China.In 2010-2011, we recruited MSM (age range 18-61; median 28 years) through peer volunteers, collected demographic/behavioral information via interviewer-administrated questionnaires. Trained health workers swabs for HPV genotyping by PCR blood samples HIV/syphilis serologies.We obtained specimens from 212 459 HIV-uninfected participants. Among 82.1% were HPV-infected vs. 57.5% (p<0.01). had the greatest likelihood multiple types: 17.9% uninfected; 36.3% one type; 36.8% 2-3; 9.0% ≥4. Oncogenic was higher HIV- infected (61.3%) than participants (39.7%; p<0.01). reporting always using condoms during insertive intercourse (past 6 months) less likely be (OR=0.49, 95%CI: 0.31-0.77). infection associated unprotected receptive months; OR=1.92, 1.19-3.11) being forced (previous year; OR=3.32, 1.10-10.0). Multivariable logistic analysis suggested that oral (adjusted OR=2.12, 1.00-4.48). Syphilis occurred 55.8% HIV-infected/HPV-infected, 50.0% HIV-infected/HPV-uninfected, 19.6% HIV-uninfected/HPV-infected, 13.0% HIV-uninfected/HPV-uninfected MSM.HPV infections more common China, including oncogenic types. Unprotected independently infection. Promotion safer vaccination strongly recommended MSM.