Effects of Nitroglycerin on the Diagnostic Accuracy of Electrocardiogram-gated Coronary Computed Tomography Angiography

• DOI: 10.1097/rct.0b013e318059befa
• Publication Date: 2008-01-24T08:01:13Z
• Authors: Eun Ju Chun; Whal Lee; Young Hoon Choi; Bon-Kwon Koo; Sang Il Choi; Hwan Jun Jae; Hyo-Cheol Kim; Young Ho So; Jin Wook Chung; Jae Hyung Park
• Keywords: Computed Tomography Angiography

To evaluate the effect of nitroglycerin on diagnostic accuracy electrocardiogram-gated coronary computed tomography (CT) angiography in patients with suspected artery disease.Computed was performed 76 using a 16-slice CT scanner. Forty-six received sublingual 1 minute before scanning (the NTG group), but other 30 did not non-NTG group). No statistically significant differences were evident between these 2 groups terms clinical and demographic characteristics. Significant stenosis (> or =50% diameter reduction) as determined by evaluated according to patient-based segment-based analyses, results compared conventional angiographic findings. In addition, segments reclassified segment luminal size into proximal, mid, distal segments, accuracies approaches segments.Differences heart rate, systolic diastolic blood pressures after 1.0 +/- 2.4 beats per minute, -8.3 14.4 mm Hg, -4.6 10.6 respectively. Sensitivity, specificity, positive negative predictive values group higher than analysis (P = 0.25) < 0.05). based each segment, significantly for proximal (96.7% vs 89.7%; P 0.05).The use found be safe improve evaluation disease.