Diagnostic Accuracy and Sensitivity of Diffusion-Weighted and of Gadoxetic Acid-Enhanced 3-T MR Imaging Alone or in Combination in the Detection of Small Liver Metastasis (≤1.5 cm in Diameter)

• DOI: 10.1097/rli.0b013e31823a1495
• Publication Date: 2012-02-11T07:31:22Z
• Authors: Young Kon Kim; Min Woo Lee; Won Jae Lee; Seong Hyun Kim; Hyunchul Rhim; Jae Hoon Lim; Dongil Choi; Young-sun Kim; Kyung Mi Jang; Soon Jin Lee; Hyo Keun Lim
• Keywords: Gadoxetic acid; Gold standard (test); Data set

Purpose: To compare the diagnostic accuracy and sensitivity of combined gadoxetic acid-enhanced magnetic resonance imaging (MRI) diffusion-weighted (DWI) with each approach alone for detecting small hepatic metastases (≤1.5 cm). Materials Methods: Institutional review board approved this retrospective study waived informed patient consent. Eighty-six patients 179 liver underwent MRI including unenhanced DWI at 3.0 T. Three image sets images—gadoxetic acid set (early dynamic hepatocyte phase), set, set—were analyzed independently in consensus by 2 observers using receiver operating characteristic analysis. Results: There was a tendency toward an increased (mean, 0.965) compared that 0.911 set; 0.926 set). The showed better 97.47%/95.0%: values on per-lesion/per-patient basis) than 90.7%/83.7% 91.6%/83.0% set) (P < 0.05) both per-lesion basis per-patient basis. All similar positive predictive values. Conclusions: combination yielded detection metastasis scan sequence alone.