Magnetic Resonance–Based Estimation of Intracranial Pressure Correlates With Ventriculoperitoneal Shunt Valve Opening Pressure Setting in Children With Hydrocephalus

• DOI: 10.1097/rli.0b013e31828ad504
• Publication Date: 2013-05-21T17:30:06Z
• Authors: Marc Muehlmann; Inga K. Koerte; Ruediger P. Laube...; Denise Steffinger; Markus Lehner; Aurelia Peraud; Florian Heinen; Michael Kiefer; Maximilian Reiser; Birgit Ertl-Wagner
• Keywords: Interquartile range; Communicating hydrocephalus

The aim of this study was to investigate the relationship between pressure setting ventriculoperitoneal (VP) shunt valve and a magnetic resonance (MR)-based estimate intracranial (ICP) in children with shunt-treated hydrocephalus without clinical signs malfunction.Institutional review board approval obtained before study, all subjects and/or their legal guardians provided written informed consent. In prospective 15 consecutive patients (median age, 8.25 years; range, 2.2-18.4 6 girls 9 boys) malfunction were examined retrospectively gated phase contrast sequences quantify arterial inflow, venous outflow, cerebrospinal fluid (CSF) flow from cranial vault. ratio maximal volume change pulse gradient used derive MR-ICP. Spearman ρ test for association opening MR-ICP.Shunt settings MR-ICP positively correlated (Spearman = 0.64, P < 0.01). Median 8.67 mm Hg (interquartile range [IQR], 1.59 Hg) median VP-shunt 6.62 (IQR, 1.47 Hg). 1.9 0.73 higher than valve.There is positive correlation VP setting. systematically assessment most likely result outflow resistance within tubing system well known fluctuation rates systems.