Longitudinal Follow-up of Fibrosing Interstitial Pneumonia

• DOI: 10.1097/rti.0b013e3181e35823
• Publication Date: 2010-07-09T10:46:54Z
• Authors: Jeong-Hwa Hwang; Shigeki Misumi; Douglas Curran-Ev...; Kevin K. Brown; Hakan Sahin; David A. Lynch
• Keywords: Usual interstitial pneumonia

The aim of this study was to evaluate the prognostic implications computed tomography (CT) and physiologic variables at baseline on sequential evaluation in patients with fibrosing interstitial pneumonia.We identified 72 pneumonia (42 idiopathic disease, 30 collagen vascular disease). Pulmonary function tests CT were performed time diagnosis a median follow-up 12 months, respectively. Two chest radiologists scored extent specific abnormalities overall disease CT. Rate survival estimated using Kaplan-Meier method. Three Cox proportional hazards models constructed relationship between rate survival: model 1 included only variables, 2 serial change 3 both variables.On CT, mixed ground-glass reticular opacities (P<0.001), pure opacity (P=0.04), honeycombing (P=0.02), (P<0.001) increased group, whereas these remained unchanged group. Patients had shorter than those (P=0.03). In 1, independent predictor mortality (P=0.02). 2, progression (P=0.005). 3, predictors (P=0.001 0.002, respectively). Neither nor presence predictive survival.The its are important determinants pneumonia.