A Septal Angle Measured on Computed Tomographic Pulmonary Angiography Can Noninvasively Estimate Pulmonary Vascular Resistance in Patients With Chronic Thromboembolic Pulmonary Hypertension

• DOI: 10.1097/rti.0b013e3182541142
• Publication Date: 2012-05-03T06:52:23Z
• Authors: Min Liu; Zhan Hong Ma; Xiao Juan Guo; Shuan Kun Wang; Xiang Yun Chen; Yuan Hua Yang; Chen Wang
• Keywords: Pulmonary angiography; Cardiac catheterization; Interventricular septum

To explore the correlation between a septal angle measured on computed tomographic pulmonary angiography (CTPA) and vascular resistance (PVR) determined by right heart catheterization in patients with chronic thromboembolic hypertension (CTEPH).Eighty-six CTEPH (54 men, mean age: 53.08±12.43 y) were retrospectively reviewed, 86 sex-matched age-matched individuals without artery embolism used as control group. All underwent CTPA before catheterization. Septal was transverse images interventricular septum line joining midpoint of sternum to thoracic vertebral spinous process. Hemodynamic PVR calculated basis data from catheterization.Septal 65.27±12.24 degrees 39.43±9.79 group group, respectively, which statistically significant (t=18.139, P=0.000). The correlated positively (r=0.629, By stepwise linear regression analysis, shown be only variable (r=0.578) that independently associated levels, leading following equation: PVR=21.591×septal angle-374.641. receiver operating characteristic ≥67.55 had sensitivity 71.6% specificity 73.4% for predicting PVR≥1000 dyne s/cm an area under curve 0.739±0.055, higher than ventricular area/left (0.627±0.061) diameter ventricle/transverse left ventricle (0.612±0.060).The is useful tool estimating CTEPH.