Radiographic Evaluation of Regenerated Bone Following Poly(Lactic-Co-Glycolic) Acid/Hydroxyapatite and Deproteinized Bovine Bone Graft in Sinus Lifting

• DOI: 10.1097/scs.0b013e31827ca01a
• Publication Date: 2013-05-29T16:56:53Z
• Authors: Ruggero Rodriguez...; Saturnino Marco Lupi; Roberta Pastorino; Carlo Maiorana; Alessandra Lucchese; Silvana Rizzo
• Keywords: PLGA; Sinus lift; Glycolic acid; Sinus (botany); Bone grafting

Although numerous biomaterials are used for maxillary sinus-lift surgery, the ideal material such procedures has not yet been identified. Both heterologous and alloplastic bone substitutes have a solely osteoconductive effect lack osteoinductive properties of morphogenetic proteins typical autologous bone. Our group assessed new graft material, poly(lactic-co-glycolic) acid/hydroxyapatite (PLGA/HA), implanted in human model surgery. For this prospective, random, double-blind trial, we deproteinized bovine (DBB) as comparison material. Radiographic vertical height density were at approximately 28 weeks after grafting using cone-beam computed tomography. The dimension regenerated was equivalent between 2 groups. PLGA/HA significantly lower than that obtained with DBB. Despite clinical assessments demonstrating sufficient characteristics use DBB provided greater an grafted Further studies needed to supplement radiologic findings histologic micromorphometric examinations.