How to Choose the Ideal Renal Replacement Therapy in Sepsis?

• DOI: 10.1097/shk.0b013e31828fafa6
• Publication Date: 2013-03-12T12:43:13Z
• Authors: Thiago Corsi Fili...; Marcelino de Souz...
• Keywords: Renal replacement therapy

Sepsis is the main cause of acute kidney injury (AKI) among individuals hospitalized in intensive care units. Acute an independent risk factor for mortality, and its occurrence increases complexity cost treatment. However, pathophysiological mechanisms AKI remain unclear. Hemodynamic, vascular, tubular, cellular, inflammatory, oxidative processes are involved. Individuals with generally have various comorbidities elderly hypercatabolic on vasopressors mechanical ventilation. Dialysis treatment AKI. Although there no clear benefit any specific dialysis modality, these patients initially instructed to use continuous methods, especially most severe cases multiple organ system dysfunctions those who display signs hemodynamic instability. Recent studies demonstrate that should receive a dose at least 25 mL · kg h.