A Comparative Study of the Long-term Outcomes After Laparoscopy-assisted and Open Left Lateral Hepatectomy for Hepatocellular Carcinoma

• DOI: 10.1097/sle.0b013e3181bc4091
• Publication Date: 2009-10-14T08:20:43Z
• Authors: Yuichi Endo; Masayuki Ohta; Atsushi Sasaki; Seiichiro Kai; Hidetoshi Eguchi; Kentaro Iwaki; Kohei Shibata; Seigo Kitano
• Keywords: Male; Carcinoma, Hepatocellular; Time Factors; Liver Neoplasms; Kaplan-Meier Estimate; Middle Aged; Prognosis; 3. Good health; 03 medical and health sciences; Treatment Outcome; 0302 clinical medicine; Japan; Hepatectomy; Humans; Female; Laparoscopy; Aged; Retrospective Studies

Laparoscopic hepatectomy was initially reported in 1992. However, the reported experiences are scarce, and this operation has not been a standard procedure until now. The aims of this study were to assess our results of laparoscopy-assisted left lateral hepatectomy for hepatocellular carcinoma (HCC) and to compare them with those of open conventional procedures.From 1984 to 2002, left lateral hepatectomy for HCC less than 5 cm in diameter was carried out in 21 patients. Ten patients received a laparoscopy-assisted procedure, and remaining 11 patients received an open procedure.There were no significant differences in the operation time, blood loss, resected liver weight, and resection margin between the 2 groups. The total time that analgesics were given, body temperature on postoperative day 1, weight loss on postoperative day 7, and postoperative hospital stay in the laparoscopic group were significantly better than in the conventional group. With regard to the long-term prognosis, there were no differences in patient survival or disease-free survival rates between the 2 groups.Laparoscopy-assisted left lateral hepatectomy for HCC is superior to the conventional open surgery in terms of its short-term results and does not cause the long-term survival to deteriorate. Therefore, laparoscopic hepatectomy may be an alternative choice for treatment of HCC.