Nocturnal Hypoxia and Arterial Lactate Levels in Sleep-Related Breathing Disorders

• DOI: 10.1097/smj.0b013e3181a93897
• Publication Date: 2011-04-06T22:35:41Z
• Authors: Zeynep Zeren Ucar; Zuhre Taymaz; Ahmet Emin Erbaycu; Cenk Kirakli; Fevziye Tuksavul; Salih Zeki Guclu
• Keywords: Arterial blood; Hypoxia

Lactate may be useful in pointing out the higher risk subgroups sleep-related breathing disorders (SRBD) with various patterns of hypoxemia. We aimed to search whether morning and night lactate levels are related apnea-hypopnea, hypoventilation, hypoxemia patients SRBD compare it without (No-SRBD).Eighty suspected underwent polysomnography (PSG) testing. had obstructive sleep apnea syndrome or hypoventilation/hypoxemic conditions. Patients were control group. Measurements included pulmonary function testing, PSG, analysis arterial blood gases, before after PSG. Arterial was compared No-SRBD patients.Morning significantly group than (1.65 +/- 0.48 1.35 0.57 mmol/L, respectively) (P = 0.003). at change overnight not different between groups. After an adjustment for age, gender, body mass index, PSG apnea-hypopnea index (beta: 0.004, 95% CI: 0.000-0.008) rate sleep-time spent under 90% oxygen saturation (T90%). The following level correlated T90% 0.005, 0.000-0.010). 0.000-0.008).As a marker tissue hypoxia, used assess severity SRBD.