GerE-independent expression of cotH leads to CotC accumulation in the mother cell compartment during Bacillus subtilis sporulation

• DOI: 10.1099/mic.0.27356-0
• Publication Date: 2004-10-06T18:18:21Z
• Authors: L. Baccigalupi
• Keywords: Compartment (ship)

Evidence is presented that expression of the cotH gene, whose product required for correct assembly Bacillus subtilis spore coat, negatively controlled by transcriptional regulator GerE. Mutations in GerE-box, present promoter region, increased this which also remained elevated during late stages sporulation, when wild-type cells normally turned off. Such alterations did not significantly affect coat structure or function but caused accumulation CotC molecules mother cell compartment, most likely as a consequence CotH-mediated protection CotC.