The Association of Coronary Artery Calcium Score and Osteoporosis in Postmenopausal Women: A Cross-Sectional Study

• DOI: 10.11005/jbm.2022.29.4.245
• Publication Date: 2022-12-08T23:58:12Z
• Authors: Mojgan Asadi; Farideh Razi; Noushin Fahimfar; Shapour Shirani; Ghazal Behzad; Pooneh Salari
• Keywords: 03 medical and health sciences; 0302 clinical medicine; Original Article; 3. Good health

The association between osteoporosis, a common metabolic bone disorder, and atherosclerosis has been reported in different studies. In this study, we aimed to investigate the coronary artery calcium score (CACS) mineral density (BMD) at sites biomarkers postmenopausal women.A total of 184 participants were enrolled study. CACS BMD sites, including spinal, hip, femoral neck, measured using computed tomography angiography dual energy X-ray absorptiometry, respectively. Serum levels osteocalcin, β-C-terminal telopeptide (β-CTX), parathyroid hormone, 25-hydroxy-vitamin D measured.A negative biomarker (osteocalcin, P=0.021; β-CTX, P=0.013) was noted. univariable model showed an osteoporosis neck (P=0.03). It found that with increase 10 U CACS, odds escalates by 2% (odds ratio=1.02, 95% confidence interval, 1.002-1.03) multivariate logistic regression model, while such could not be spinal site. best cutoff point estimated 127.The results suggest women, is independently associated but detected osteoporosis. importance screening for patients cardiovascular disease implications preventive measures primary care setting highlighted considering risk factors.