Long-term COVID-19 symptoms in a large unselected population

• DOI: 10.1101/2020.10.07.20208702
• Publication Date: 2020-10-11T17:40:11Z
• Authors: Elizabeth T. Cirulli; Kelly M. Schiabor...; Stephen Riffle; Alexandre Bolze; Iva Neveux; Shaun Dabe; Joseph J. Grzymski; James T. Lu; Nicole L. Washington
• Keywords: Anosmia

It is increasingly recognized that SARS-CoV-2 can produce long-term complications after recovery from the acute effects of infection. Here, we report analysis 32 self-reported short and symptoms in a general adult population cohort comprised 357 COVID-19+ cases, 5,497 SARS-CoV-2-negative controls, 19,095 non-tested individuals. The majority our cases are mild, with only 9 having been hospitalized. Our results show 36.1% have lasting longer than 30 days, 14.8% still at least one symptom 90 days. These numbers higher for who were initially more ill, 44.9% days 20.8% but even very mild asymptomatic 21.3% persist or longer. In contrast, 8.4% participants untested develop new due to any illness during same study period. most enriched those COVID-19 anosmia, ageusia, difficulty concentrating, dyspnea, memory loss, confusion, chest pain, pain deep breaths. addition individuals sick symptoms, additionally observe an initial dyspnea significantly likely symptoms. Importantly, finds overall level important variable account when assessing statistical significance associated COVID-19. provides baseline which understand frequency demonstrates that, although severe illness, courses infection increased risk complications.