Disrupted dynamic network reconfiguration of the executive and reward networks in internet gaming disorder: Why IGD subjects cannot control their gaming cravings

• DOI: 10.1101/2021.09.29.462308
• Publication Date: 2021-10-01T17:12:36Z
• Authors: Min Wang; Hui Zheng; Weiran Zhou; Bo Yang; Lingxiao Wang; Shuaiyu Chen; Guang-Heng Dong
• Keywords: Immunoglobulin D

Abstract Background Studies have shown that people with internet gaming disorder (IGD) show impaired executive control over their cravings; however, the neural mechanisms underlying this process remain unknown. In addition, these conclusions were based on hypothesis brain networks temporally stationary and neglected changes in cognitive processes. Methods Resting-state fMRI data collected from 402 subjects (162 IGD 240 recreational game users (RGUs)). The community structure (recruitment integration) of network basal ganglia (BGN, representing reward network) patients healthy controls analyzed compared. Mediation effects among different networks. Results When compared to RGUs, had a lower recruitment coefficient within right (ECN). Further analysis showed only male coefficient. integration ECN mediated relationship between coefficients both BGN RGUs. Conclusions Subjects than feature was observed subjects, making them less efficient at impulse control. meditation results suggest top-down mechanism is missing IGD. All findings could explain why cravings.