Sperm Toolbox – A selection of small molecules to study human spermatozoa

• DOI: 10.1101/2023.05.02.539126
• Publication Date: 2023-05-02T22:35:14Z
• Authors: Franz S. Gruber; Anthony Richardson; Zoe C. Johnston; Rachel Myles; Neil Norcross; David Day; Irene Georgiou; Laura Sesma Sanz; Caroline Wilson; Kevin D. Read; Sarah Martins da ...; Christopher L. R....; Ian H. Gilbert; Jason R. Swedlow
• Keywords: Toolbox

Abstract Male contraceptive options and infertility treatments are limited. To help overcome these limitations we established a small molecule library as toolbox for assay development screening campaigns using human spermatozoa. We have profiled all compounds in our automated high-throughput platform provide the dataset, which allows direct side-by-side comparisons of compound effects assays live