Coelomata and Not Ecdysozoa: Evidence From Genome-Wide Phylogenetic Analysis

• DOI: 10.1101/gr.1347404
• Publication Date: 2004-01-05T22:39:03Z
• Authors: Yuri I. Wolf; Igor B. Rogozin; Eugene V. Koonin
• Keywords: Maximum parsimony; Phylogenomics

Relative positions of nematodes, arthropods, and chordates in animal phylogeny remain uncertain. The traditional tree topology joins arthropods with a coelomate clade, whereas which lack coelome, occupy basal position. However, the current leading hypothesis, based on phylogenetic trees for 18S ribosomal RNA several proteins, nematodes clade molting animals, Ecdysozoa. We performed analysis over 500 sets orthologous are represented plants, fungi, using maximum likelihood, parsimony, distance methods. Additionally, to increase statistical power tests, same methods were applied concatenated alignments subunits eight conserved macromolecular complexes. majority methods, when most clusters, both individual, grouped fly humans exclusion nematode, support phylogeny. Trees also constructed information insertions deletions combinations domains multidomain presence-absence species clusters orthologs. All these approaches supported showed concordance between evolution protein sequences higher-level evolutionary events, such as domain fusion or gene loss.