High-Resolution Microscopic Ghost Imaging for Bioimaging

• DOI: 10.1103/physrevapplied.20.014028
• Publication Date: 2023-07-13T14:51:26Z
• Authors: Xiao-Hui Zhu; Yan-Feng Bai; Wei Tan; Li-Yu Zhou; Xian-Wei Huang; Tong-Ji Jiang; Teng Jiang; Su-Qin Nan; Xi-Quan Fu
• Keywords: Ghost Imaging

A label-free, low-photodamage, low-cost, and in vivo high-resolution microscopic imaging technique has been challenging to develop. Ghost (GI) is a computational protocol with the spatially nonlocal property, which enables low-light imaging. Considering advantages of GI, we propose method, called ghost (HRMGI), achieve by simply demagnifying signal beam. The analytical formulas for resolution depth field (DOF) HRMGI are provided. Experimental results show that system can have 10.5 times higher than conventional exceed pixel size limit multipixel detectors, 58 greater DOF traditional diffraction-limited optical (TDLO) system. To present performance HRMGI, blood vessels within an ovarian section also imaged. proposed method expected facilitate development bioimaging techniques promote practical application GI.