External validation of the Simplified Mortality Score for the Intensive Care Unit (SMS‐ICU)

• DOI: 10.1111/aas.13422
• Publication Date: 2019-07-05T04:59:25Z
• Authors: Anders Granholm; Anders Perner; Mette Krag; Søren Marker; Peter Buhl Hjortrup; Nicolai Haase; Lars Broksø Holst; Marie Oxenbøll Co...; Aksel Karl Georg ...; Morten Hylander M...
• Keywords: SAPS II; SOFA score

Background The Simplified Mortality Score for the Intensive Care Unit (SMS‐ICU) is a clinical prediction model, which estimates risk of 90‐day mortality in acutely ill adult ICU patients using 7 readily available variables. We aimed to externally validate SMS‐ICU and compare its discrimination with existing models used as outcome. Methods validated data from 3282 included Stress Ulcer Prophylaxis trial, randomised factors gastrointestinal bleeding prophylactic pantoprazole or placebo 33 ICUs Europe. assessed discrimination, calibration overall performance compared commonly more complex SAPS II SOFA scores. Results at day 90 was 30.7%. (area under receiver operating characteristic curve) 0.67 (95% CI: 0.65‐0.69), 0.68 0.66‐0.70, P = 0.35) 0.63 0.61‐0.65, < 0.001) score. Calibration (intercept slope) 0.001 0.786, respectively, Nagelkerke's R 2 (overall performance) 0.06. proportions missing SMS‐ICU, scores were 0.2%, 8.5% 6.8%, respectively. Conclusions Discrimination this cohort poor, but similar better than that score markedly less data.