The role of novelty seeking as a predictor of substance use disorder outcomes in early adulthood

• DOI: 10.1111/add.13838
• Publication Date: 2017-04-07T13:37:34Z
• Authors: James A. Foulds; Joseph M. Boden; Giles M. Newton-H...; Roger T. Mulder; L. John Horwood
• Keywords: Quartile

Background and aims There has been a great deal of evidence showing that high novelty seeking (NS) is risk factor for the development substance use disorders (SUDs). However, possible causal role NS in SUDs unconfirmed. The aim this study was to examine associations between at age 16 from ages 18 35 years, net series covariate factors. Design Longitudinal birth cohort. Setting Christchurch, New Zealand. Participants General community sample with sizes ranging n = 1011 (age 21) 962 35). Measurements Composite International Diagnostic Interview used derive DSM-IV diagnoses alcohol, nicotine, cannabis other illicit four time intervals 35. measured using Tridimensional Personality Questionnaire. Findings An increase associated increases prevalence all 18–35. Following adjustment broad range factors, estimated effect (odds ratios) were reducing magnitude, but remained moderate large. Adjusted odds ratios highest quartile compared lowest 2.0 [95% confidence interval (CI) 1.5, 2.7] alcohol; 1.8 (95% CI 1.3, 2.7) nicotine; 3.6 2.4, 5.6) 5.1 2.9, 9.2) substances. Conclusions association not explained by common underlying individual factors environmental exposures. This consistent view may play disorders.