Management of anaphylaxis due to COVID‐19 vaccines in the elderly

• DOI: 10.1111/all.14838
• Publication Date: 2021-04-03T02:20:55Z
• Authors: Jean Bousquet; Ioana Agache; Hubert Blain; Marek Jutel; Maria Teresa Ventura; Margitta Worm; Stefano Del Giacco; Athanasios Benetos; Beatrice Maria Bilo; Wienczyslawa Czar...; Amir Hamzah Abdul...; Mona Al‐Ahmad; Elizabeth Angier; Isabella Annesi‐M...; Marina Atanaskovi...; Claus Bachert; Annick Barbaud; Anna Bedbrook; Kazi S. Bennoor; Elena Camelia Ber...; Carsten Bindslev‐...; Sergio Bonini; Sinthia Bosnic‐An...; Knut Brockow; Luisa Brussino; Paulo Camargos; G. Walter Canonica; Victoria Cardona; Pedro Carreiro‐Ma...; Ana Carriazo; Thomas Casale; Jean‐Christoph Ca...; Lorenzo Cecchi; Antonio Cherubini; George Christoff; Derek K. Chu; Alvaro A. Cruz; Dejan Dokic; Yehia El‐Gamal†; Motohiro Ebisawa; Bernadette Eberlein; John Farrell; Montserrat Fernan...; Wytske J. Fokkens; Joao A. Fonseca; Yadong Gao; Gaëtan Gavazzi; Radoslaw Gawlik; Asli Gelincik; Bilun Gemicioğlu; Maia Gotua; Olivier Guérin; Tari Haahtela; Karin Hoffmann‐So...; Hans Jürgen Hoffmann; Maja Hofmann; Martin Hrubisko; Maddalena Illario; Carla Irani; Zhanat Ispayeva; Juan Carlos Ivanc...; Kaja Julge; Igor Kaidashev; Musa Khaitov; Edward Knol; Helga Kraxner; Piotr Kuna; Violeta Kvedariene; Antti Lauerma; Lan T. T. Le; Vincent Le Moing; Michael Levin; Renaud Louis; Olga Lourenco; Vera Mahler; Finbarr C. Martin; Andrea Matucci; Branislava Milenk...; Stéphanie Miot; Emma Montella; Mario Morais‐Almeida; Charlotte G. Mortz; Joaquim Mullol; Leyla Namazova‐Ba...; Hugo Neffen; Kristof Nekam; Marek Niedoszytko; Mikaëla Odemyr; Robyn E. O’Hehir; Yoshitaka Okamoto; Markus Ollert; Oscar Palomares; Nikolaos G. Papad...; Petr Panzner; Giovanni Passalacqua; Vincenzo Patella; Mirko Petrovic; Oliver Pfaar; Nhân Pham‐Thi; Davor Plavec; Todor A. Popov; Marysia T. Recto; Frederico S. Rega...; Jacques Reynes; Regina E. Roller‐...; Yves Rolland; Antonino Romano; Carmen Rondon; Menachem Rottem; Philip W. Rouadi; Nathalie Salles; Boleslaw Samolinski; Alexandra F. Santos; Faradiba S Sarquis; Joaquin Sastre; Jos M. G. A. Schols; Nicola Scichilone; Anna Sediva; Mohamed H. Shamji; Aziz Sheikh; Isabel Skypala; Sylwia Smolinska; Milena Sokolowska; Bernardo Sousa‐Pinto; Milan Sova; Rafael Stelmach; Gunter Sturm; Charlotte Suppli ...; Ana Maria Todo‐Bom; Sanna Toppila‐Salmi; Ioanna Tsiligianni; Maria Torres; Eva Untersmayr; Marilyn Urrutia P...; Arunas Valiulis; Joana Vitte; Alessandra Vultaggio; Dana Wallace; Jolanta Walusiak‐...; De‐Yun Wang; Susan Waserman; Arzu Yorgancioglu; Osman M. Yusuf; Mario Zernotti; Mihaela Zidarn; Tomas Chivato; Cezmi A. Akdis; Torsten Zuberbier; Ludger Klimek
• Keywords: Male; COVID-19 vaccines; older (adults; GUIDELINES; 0302 clinical medicine; [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases; Medicine and Health Sciences; info:eu-repo/classification/ddc/618; Immunology and Allergy; [SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases; [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology; MESH: Aged; RISK; Vaccines; [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases; people); EPINEPHRINE; General medicine, internal medicine and other clinical medicine; [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system; 3. Good health; [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology; [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases; COVID -19 vaccines; [SDV.MP.PAR] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology; older (adults/people); Risk; COVID-19 Vaccines; Epinephrine; MESH: Covid-19; MESH: Epinephrine; Anaphylaxis / etiology; Immunology; adrenaline; anaphylaxis; COVID-19 vaccines; older (adults/people); Aged; COVID-19 Vaccines; Epinephrine; Humans; Male; SARS-CoV-2; Anaphylaxis; COVID-19; Guidelines; Adrenaline; 03 medical and health sciences; [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system; Anaphylaxis/etiology; anaphylaxis; Humans; MESH: SARS-CoV-2; [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology; Anaphylaxis; Older - Adults/people; Aged; MESH: Humans; adrenaline; SARS-CoV-2; adrenaline, anaphylaxis, COVID-19 vaccines, older (adults/people); COVID-19; [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology; Anaphylaxis / prevention & control; 300; MESH: Male; MESH: Anaphylaxis; Older; [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology; MESH: Covid-19 vaccines; Older (adults/people)

Older adults, especially men and/or those with diabetes, hypertension, obesity, are prone to severe COVID-19. In some countries, older particularly residing in nursing homes, have been prioritized receive COVID-19 vaccines due high risk of death. very rare instances, the can induce anaphylaxis, and management anaphylaxis people should be considered carefully. An ARIA-EAACI-EuGMS (Allergic Rhinitis its Impact on Asthma, European Academy Allergy Clinical Immunology, Geriatric Medicine Society) Working Group has proposed recommendations for adults receiving vaccines. Anaphylaxis is extremely (from 1 per 100,000 5 million injections). Symptoms similar younger but they tend more patients. Adrenaline mainstay treatment readily available. A flowchart manage