The relationship of serum testosterone levels with the clinical course and prognosis of COVID‐19 disease in male patients: A prospective study

• DOI: 10.1111/andr.13081
• Publication Date: 2021-07-19T17:39:30Z
• Authors: Ahmet Emre Cinisl...; Nazan Cinislioglu; Saban Oguz Demird...; Emre Sam; Fatih Akkas; Mehmet Sefa Altay; Mustafa Utlu; Irem Akin Sen; Fatih Yildirim; Seyfi Kartal; Hasan Riza Aydin; Ibrahim Karabulut; Isa Ozbey
• Keywords: Outpatient clinic

A potential role of testosterone among sex hormones has been hypothesized in identifying sex-related differences the clinical consequences severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Due to high global prevalence hypogonadism, relationship between hypogonadism and SARS-CoV-2 infection outcomes deserves an in-depth study.The present study aimed investigate serum with other laboratory parameters on prognosis coronavirus disease-19 (COVID-19) male patients COVID-19 diagnosis.This prospective cohort included 358 diagnosed 92 negative admitted urology outpatient clinics as a control group. The were divided into groups according (mild-moderate group), lung involvement chest computed tomography (<50% >50%), intensive care unit needs, survival.The measured total level group was found be significantly lower than that (median, 140 ng/dl; range, 0.21-328, 322 median, 125-674, p < 0.001, respectively). TT levels statistically compared mild-moderate 85.1 0.21-532, 315 0.88-486, respectively), need who did not 64.0 0.21-337, 286 0.88-532 died survivors 82.9 2.63-165, 166 respectively).Our data are compatible low playing pathogenesis disease Covid-19 poor mortal course may guide clinicians determining disease.