Representation of the elderly in trials of laparoscopic surgery for colorectal cancer

• DOI: 10.1111/codi.12806
• Publication Date: 2014-10-20T15:12:14Z
• Authors: A. H. W. Schiphorst; A. Pronk; I. H. M. Borel Ri...; M. E. Hamaker
• Keywords: Colorectal Surgery

Most patients with colorectal cancer are elderly, but there few data on the optimal surgical treatment for this age group and most studies observational. We have reviewed characteristics of randomized trials reporting laparoscopic surgery to determine degree which elderly represented.A search was conducted NIH clinical trial registry ISRCTN register cancer. Trial end-points were extracted from website supplemented by published results where available.Of 52 protocols majority did not state any restrictions regarding cardiac [40 (77%)] or pulmonary function [41 (79%)]. More than half [30 (58%)] had no American Society Anesthesiologists score. Twenty-three (44%) excluded either simply comorbidity organ function. When an upper limit set, restriction function, indicating that chronological rather physical condition taken as reason exclusion. In 45 (86%) average participants < 70 years, details concurrent disease given.Participation in is very limited. This should be remedied future if adequate information obtained.