Protocol of the LATFIA trial (Laser Assisted Treatment of Fistula in Ano): a multicentre, prospective, randomized controlled trial comparing fistula‐tract laser closure (FiLaC™) with rectal advancement flap for high trans‐sphincteric fistulas

• DOI: 10.1111/codi.16951
• Publication Date: 2024-03-19T03:58:14Z
• Authors: Marie Gaillard; Sylvie Van den Br...; Bart Op de Beeck; Kristien Wouters; Jasper Stijns; Dirk Van de Putte; Ben Gys; Bert Houben; Els Van Dessel; Gabriele Bislenghi; Niels Komen
• Keywords: Gold standard (test); Clinical endpoint

Anal fistula is one of the most common anal diseases, affecting between 1 and 3 per 10 000 people year. Symptoms have a potentially severe effect on patient's quality life. Surgery mainstay treatment, aiming to cure preserve sphincter function. Rectal advancement flap (RAF) currently gold standard treatment but has recurrence rates varying 20% 50% might lead disturbance continence. The aim trial described in this work discover if minimally invasive tract laser closure (FiLaC™) technique could achieve higher healing better functional outcome than RAF.