Diagnostic algorithm of magnifying endoscopy with crystal violet staining for non‐ampullary duodenal epithelial tumors

• DOI: 10.1111/den.13640
• Publication Date: 2020-01-30T07:23:42Z
• Authors: Yosuke Toya; Masaki Endo; Tomofumi Oizumi; Risaburo Akasaka; Shunichi Yanai; Keisuke Kawasaki; Shotaro Nakamura; Makoto Eizuka; Yasuko Fujita; Noriyuki Uesugi; Kazuyuki Ishida; Tamotsu Sugai; Takayuki Matsumoto
• Keywords: Kappa

Objectives Little is known about the usefulness of magnifying endoscopy with crystal violet staining (ME‐CV) for diagnosis duodenal tumors. We assessed ability ME‐CV to distinguish Vienna classification (VCL) category 4/5 (C4/5) from 3 (C3) non‐ampullary epithelial tumors (NADETs). Methods A total 76 NADETs were studied. retrospectively analyzed diagnostic values white light (WLE) scoring system and algorithm receiver operating characteristic (ROC) curves, three endoscopists calculated sensitivity, specificity, accuracy, area under curve (AUC) each. The tested among overall subgroups gastric, gastrointestinal or intestinal mucin phenotypes. Inter‐observer agreement results was also calculated. Results According VCL, 54 lesions (71.1%) regarded as C3 22 (28.9%) C4/5. accuracy AUC higher than those WLE (63.6 vs 54.5, 85.2 75.9, 78.9 69.7, 0.744 0.652, respectively). agreements both moderate (kappa 0.45 0.41). had gastric phenotypes NADETs. Conclusions appropriate C4/5