Mediterranean diet and diabetes risk in a cohort study of individuals with prediabetes: propensity score analyses

• DOI: 10.1111/dme.14768
• Publication Date: 2021-12-12T06:16:25Z
• Authors: Lucía Cea‐Soriano; José Pulido; Josep Franch‐Nadal; Juana M. Santos; Manel Mata‐Cases; Javier Díez‐Espino; Antonio Ruiz‐García; Enrique Regidor
• Keywords: Prediabetes; Mediterranean Diet; Glycated hemoglobin

Randomized controlled trials have demonstrated the efficacy of several dietary patterns plus physical activity to reduce diabetes onset in people with prediabetes. However, there is no evidence on effect from Mediterranean diet progression prediabetes diabetes. We aimed evaluate high adherence risk individuals prediabetes.Prospective cohort study Spanish Primary Care setting. A total 1184 participants based levels fasting plasma glucose and/or glycated hemoglobin were followed up for a mean 4.2 years. 210 developed type 2 during follow up. Hazard ratios estimated by Cox proportional regression models associated versus low/medium diet. Different propensity score methods used control potential confounders.Incidence rate was 2.9 4.8 per 100 persons-years. The hazard adjusted and inverse probability weighting (IPW) had identical magnitude: 0.63 (95% confidence interval, 0.43-0.93). ratio model using matching 1:2 0.56 0.37-0.84).These analyses suggest that reduces