Insomnia disorder: clinical and research challenges for the 21st century

• DOI: 10.1111/ene.14784
• Publication Date: 2021-02-23T07:13:30Z
• Authors: Luigi Ferini‐Strambi; Reto Auer; Bjørn Bjorvatn; Vincenza Castronovo; Oscar Franco; Luca Gabutti; Andrea Galbiati; Goeran Hajak; Ramin Khatami; Tsuyoshi Kitajima; Doug McEvoy; Christoph Nissen; Michael Perlis; Dirk A. Pevernagie; Winfried Randerath; Dieter Riemann; Giovanni Rizzo; Eus Van Someren; Alexandros Vgontzas; Fabrizio Barazzoni; Claudio Bassetti
• Keywords: Neurocognitive

Abstract Background and purpose Insomnia is a common debilitating disorder that frequently associated with important consequences for physical health well‐being. Methods An international expert group considered the current state of knowledge based on most relevant publications in previous 5 years, discussed challenges field insomnia identified future priorities. Results The association trajectories subsequent quality life, mortality should be investigated large populations. Prospective economics studies by separating costs driven specifically attributable to its long‐term effects are needed. Ignoring heterogeneity patients leads inadequate diagnosis inefficient treatment. Individualized interventions promoted. More data needed both impact sleep overnight effects, such as emotion regulation, potential compensatory effort counteract diurnal impairments. Another gap definition neurocognitive deficits compared normal subjects after chronic loss. There also number key gaps related Expert guidelines indicate cognitive–behavioural therapy first‐line They neglect, however, reality major healthcare providers. role combined therapy, plus pharmacological treatment, evaluated more extensively. Conclusion Whilst might affect proportions population, there significant epidemiological/clinical/research carried out date. In particular, identification different phenotypes could allow cost‐effective efficient therapies.