Outcome prediction in patients with acute repetitive seizures: Application of the Status Epilepticus Severity Score

• DOI: 10.1111/epi.14061
• Publication Date: 2018-03-30T10:25:05Z
• Authors: Sebastian Szklener; Magdalena Godek; Agnieszka Korchut; Luiza Balicka‐Adamik; Robert Rejdak; Andrea O. Rossetti; Konrad Rejdak
• Keywords: Adult; Male; Middle Aged; Prognosis; Severity of Illness Index; 3. Good health; 03 medical and health sciences; Status Epilepticus; Treatment Outcome; 0302 clinical medicine; ROC Curve; Area Under Curve; Humans; Anticonvulsants; Female

Acute repetitive seizures (ARS) pose a risk of hospital admission with status epilepticus and mortality threat, which underscores the need for early prediction clinical course. Unfortunately, little attention has been given to ARS in this context, even though we possess appropriate predictive tools stages epilepticus. Therefore, main aim study was assess prognostic value Status Epilepticus Severity Score (STESS) population patients ARS. The included 200 patients. Almost half had achieved seizure cessations after diazepam administration, whereas 19.5% progressed despite antiepileptic drug treatment. Mortality reached 10.5% total population. receiver operating characteristic (ROC) curve death by STESS an area under (AUC) 0.901, optimal cutoff point discrimination ≥2 (sensitivity 0.95, specificity 0.71, Youden index 0.66). Hosmer-Lemeshow indicated good calibration (chi-square goodness-of-fit test = 3.24; P .919). shows excellent effectiveness prognosis course may be valuable tool proper planning diagnostic therapeutic activities