Polypharmacy and gait speed in individuals with mild cognitive impairment

• DOI: 10.1111/ggi.13688
• Publication Date: 2019-05-20T10:28:00Z
• Authors: Hiroyuki Umegaki; Madoka Yanagawa; Hitoshi Komiya; Masaki Matsubara; Chisato Fujisawa; Yusuke Suzuki; Masafumi Kuzuya
• Keywords: Clinical Dementia Rating

Aim Polypharmacy has been reported to be associated with poor outcomes, including falls and frailty, in older populations. Past studies have found that slower walking speed is a good predictor of progression frank dementia mild cognitive impairment (MCI). Some the general population polypharmacy was gait speed; however, it remains elucidated whether affects even individuals MCI, who already some deterioration compared cognitively preserved individuals. The current study explored association between number medications adults MCI Clinical Dementia Rating score 0.5. Methods A total 128 were included present study. participants divided into three groups according they taking: up four non‐polypharmacy; five nine polypharmacy; ≥10 hyperpolypharmacy. background characteristics by analysis variance for numerical numbers, χ 2 categorical factors. Multiple regression logistic applied investigate status or medications. Results Gait significantly negatively hyperpolypharmacy Slow (<1 m/s) also Conclusions We slow MCI. Geriatr Gerontol Int 2019; 19: 730–735 .